Artificial Intelligence and Self-Driving Laboratories for Scientific Discovery and Tech-Transfer

Bojdys,* M. J. Zenodo 2025. DOI: 10.5281/zenodo.14739257

Key Findings

  • Self-driving labs speed R&D, reduce costs, ensure reproducibility, and address workforce gaps through AI-driven automation.
  • FAIR data and modern IP frameworks empower academia-industry collaborations, accelerating lab-to-market journeys.
  • Massive AI and HPC investments can revolutionize R&D if guided by ethical governance, open access, and sustainable principles.

Self-driving laboratories (SDLabs) represent a transformative approach to research and development (R&D), combining artificial intelligence (AI), robotics, and digital tools to revolutionize workflows in deep-tech industries (e.g. materials, chemistry, biotechnology), and beyond. By automating experiments and decision-making processes, SDLabs enable faster and more efficient scientific discovery, reduce costs, and enhance reproducibility. This white paper explores SDLabs’ potential, from accelerating innovation to addressing sustainability challenges, while highlighting critical ethical, cultural, and technological considerations. Furthermore, it examines the role of AI in technology transfer, showcasing success stories and actionable strategies for leveraging these advancements across sectors.

Is Germany’s Political Landscape Jeopardizing the Future of Science and Innovation?

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Political instability, funding freezes, and bureaucratic hurdles are threatening Germany’s position as a global leader in science and technology. This article explores how recent disruptions within the Federal Ministry of Education and Research (BMBF) are impacting transformative initiatives like T!Raum and DATI, and examines what’s at stake for Germany’s scientific future.

Continue reading Is Germany’s Political Landscape Jeopardizing the Future of Science and Innovation?

Gefährdet die politische Landschaft Deutschlands die Zukunft von Wissenschaft und Innovation?

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Politische Instabilität, Finanzierungssperren und bürokratische Hürden bedrohen Deutschlands Position als globaler Vorreiter in Wissenschaft und Technologie. Dieser Artikel beleuchtet, wie jüngste Turbulenzen im Bundesministerium für Bildung und Forschung (BMBF) transformative Initiativen wie T!Raum und DATI beeinflussen und was dies für die Zukunft der Wissenschaft in Deutschland bedeutet.

Continue reading Gefährdet die politische Landschaft Deutschlands die Zukunft von Wissenschaft und Innovation?

Empowering sustainable energy with advanced battery technology: From lab to market

We are excited to share an insightful interview with Barbora Balcarova and Michael J. Bojdys from MANA.energy, a startup driving innovation in sustainable energy with advanced battery technology.

The article is online here: https://analyticalscience.wiley.com/content/article-do/empowering-sustainable-energy-advanced-battery-technology

Read the full article on page 14 in Wiley Analytical Science Magazine Volume 4 – June/24: https://analyticalscience.wiley.com/content/magazine-do/wiley-analytical-science-magazine-june-issue-2024

One-pot Synthesis of High-capacity Sulfur Cathodes via In-situ Polymerization of a Porous Imine-based Polymer

Li,* G.; Liu, Y.; Schultz, T.; Exner, M.; Muydinov, R.; Wang, H.; Scheurell, K.; Huang, J.; Szymoniak, P.; Pinna, N.; Koch, N.; Adelhelm, P.; Bojdys,* M. J. Angew. Chem. Int. Ed. 2024. DOI: 10.1002/anie.202400382 [OPEN ACCESS]

Innovative research has brought us closer to sustainable battery technology with a breakthrough in sulfur-based cathodes. Traditionally, lithium-ion batteries—central to electronics and electric vehicles—rely on scarce materials like cobalt. Sulfur offers a greener alternative due to its abundance and impressive theoretical capacity of 1675 mAh g-1.

A major challenge with sulfur has been the “sulfur-shuttle” effect, where sulfur’s mobility leads to rapid battery degradation. However, a recent study introduces a novel solution: encapsulating sulfur within a microporous, imine-based polymer network directly on the current collector. This one-pot synthesis approach not only streamlines production but also significantly boosts battery performance.

This innovative cathode design enables selective electrolyte and Li-ion transport while robustly containing the sulfur, delivering high performance across discharge rates—from 1360 mAh g-1 at 0.1 C to 807 mAh g-1 at 3 C. Advanced analysis through DFT calculations and operando Raman spectroscopy has shown that the polymer’s imine groups enhance polysulfide binding, effectively reducing degradation.

This breakthrough paves the way for sulfur-based cathodes to become a viable alternative to metal-based ones, marking a significant step toward greener, high-performance battery technologies. Keep an eye on this space—sulfur could be the future of batteries!

[Press-release] ICSMB “Revolutionary development in the field of battery technology through innovative sulphur cathodes”

DOI: 10.1002/anie.202400382

Molecular Mobility and Gas Transport Properties of Mixed Matrix Membranes Based on PIM‑1 and a Phosphinine Containing Covalent Organic Framework

Emamverdi, F.; Huang, J.; Razavi, N. M.; Bojdys, M. J.; Foster, A. B.; Budd, P. M.; Schönhals, A. Macromolecules 2024. DOI: 10.1021/acs.macromol.3c02419

Researchers have developed a groundbreaking membrane technology by incorporating a novel covalent organic framework (COF), CPSF-EtO, into polymers with intrinsic microporosity (PIM-1), enhancing gas separation efficiency and membrane longevity. This innovative approach led to a significant 50% increase in carbon dioxide permeability and a 27% improvement in CO2/N2 selectivity, crucial for applications in carbon capture and natural gas purification. The addition of CPSF-EtO not only facilitates gas transport by creating additional free volume within the membrane but also counteracts the physical aging that typically diminishes membrane performance over time.

This advancement in membrane technology marks a significant leap forward, offering a more sustainable and cost-effective solution for gas separation processes, with promising implications for environmental protection and resource utilization.

Structure and molecular mobility of phosphinine-based covalent organic frameworks – glass transition of amorphous COFs

Emamverdi, F.; Huang, J.; Szymoniak, P.; Bojdys, M. J.; Böhning, M.; Schönhals, A. Mater. Adv. 2024. DOI: 10.1039/d3ma01123b

Scientists have identified a glass transition in amorphous covalent organic frameworks (COFs), a finding that challenges the conventional understanding of these materials. The research focused on two novel phosphinine-based COFs, distinguished by methoxy (CPSF-MeO) and ethoxy (CPSF-EtO) groups, revealing significant differences in their thermal behavior and structure.

The analysis demonstrated that CPSF-EtO transitions into a glass state at a temperature approximately 100 K higher than CPSF-MeO, attributed to the different ways in which the molecular layers stack and interact. This behavior was confirmed through both calorimetry and dielectric measurements, suggesting that these amorphous COFs exhibit glass-like properties.

This breakthrough opens up new possibilities for the application of COFs in various technologies, including gas storage and separation, by harnessing their unique structural and thermal characteristics.

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